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After reconstitution, use solutions promptly under appropriate laboratory conditions and avoid repeated freeze–thaw cycles
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Furthermore, it increased itaconic acid production through inhibition of immune response gene 1 (IRG1) and succinate dehydrogenase (SDH) activity—an enzyme responsible for the negative regulation of HIF-1α/NLRP3 signaling and, consequently, for the polarization of M1 to M2 macrophages [281]
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