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Patients with endometriosis have decreased quality and quantity of oocytes and embryos, decreased implantation and pregnancy rates, and increased rates of spontaneous abortion Patients suffered from endometriosis showed lower ovarian reserved ( Multiple factors in the pathogenesis of endometriosis-associated infertility: an overview Mechanical factors Multiple factors have been implicated as contributing to infertility of patients with endometriosis

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The flip side is that someone with more microbial folate and a moderate dietary intake of folate may have no issues from MTHFR variants