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This response was absent in CFBE41o − F508del cells treated with VX-809 and primary human bronchial epithelial cells, implicating CFTR-independent mechanisms for the effect of ARINA-1 on cystic fibrosis mucus
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11 Vitamins and Other Metabolic Agents Simvastatin inhibits 3-hydroxy-3-methylglutaryl (HMG) coenzyme A reductase, the enzyme that promotes endogenous production of cholesterol
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