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Western blot analysis of GSS, a GSH de novo synthesis enzyme in brain... | Download Scientific Diagram

Similarly, chronic metabolic diseases such as diabetes impair glucose transport, increase oxidative stress, and trigger neuroinflammation, factors that are known to impair sleep-wake regulation and exacerbate age-related cognitive decline (Muriach et al., 2014

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These TRPs are expressed not only in nerve endings but also in the endothelium and keratinocytes ( Figure 3 Several studies suggest that adenosine 5’-triphosphate (ATP), a purinergic nucleotide and neurotransmitter, also participates in rosacea pathogenesis by regulating vascular tone and immune responses ( Rosacea patients exhibit heightened responses to heat or stress, leading to increased sweating and cutaneous vasodilation ( The aforementioned hypothesis remains to be confirmed through studies on the associations of these vasoactive neurotransmitters with rosacea