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In summary, cancer progression is closely linked with oxidative stress, with SOD playing a key role in mitigating ROS-induced DNA damage and inflammation
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Given the described D1R-GHSR1a dimer, one could propose that GHSR antagonism reduces the reinforcing effects of drugs of abuse like alcohol, nicotine, and cocaine by reducing D1 receptor signaling produced by the D1R-GHSR1a dimer
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