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Why Results Vary So Much Several factors explain why studies produce different outcomes: Formulation differences affect how much glutathione your body actually absorbs Dosage amounts range widely across studies, from 250 mg to 1,000 mg daily Individual health status, including baseline oxidative stress, changes how supplements perform Study duration varies, with some trials lasting only weeks while others run six months or longer Sample sizes are often small, limiting how confident we can be in the findings This variability is why primary care clinicians recommend a personalized approach rather than assuming one product works the same for everyone

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Therefore, a true overdose that causes toxicity is extremely rare