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Epidemiologically, up to 51.61% of obese PCOS patients develop hepatic steatosis ( At its core, PCOS is a systemic metabolic disease driven by a vicious cycle of hyperandrogenemia and IR ( The progression and manifestations of PCOS are therefore closely linked to multi-organ dysfunction, particularly involving the liver, cardiovascular system, skeletal muscle, and pancreas ( 1.3.1 Hepatic complications PCOS patients frequently present with metabolic dysfunction–associated steatotic liver disease (MASLD), with a prevalence reaching 51.61% among obese individuals
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