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hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data: Cell Reports Methods
Increasing DHFR, and thus BH4 recycling, prevented the formation of abdominal aortic aneurysms.[ref] However, in humans with DHFR variants, this recycling pathway may not work as well.[ref] Systemic inflammation, BH4 response, and vascular function: Systemic inflammation puts stress on the vascular system, leading to atherosclerosis in some people
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