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With respect to the use of GPx as a potential biomarker for MeHg exposure/poisoning, Usuki and Fujimura [111] have pointed out the plasma selenium-dependent glutathione peroxidase (GPx3) as a potential biomarker of ongoing MeHg cytotoxicity

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After metabolic pathway analysis, it was found that the antidepressant mechanism of ZZCD on CUMS rats related to the improvement of brain metabolism in Phenylalanine, tyrosine and tryptophan biosynthesis, Glutathione metabolism, Phenylalanine metabolism, Lysine degradation, Cysteine, and methionine metabolism, Tyrosine metabolism, and Tryptophan metabolism