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Briefly, after pregnant dams were anesthetized, the uterine horns were exposed, and one to two microliters of plasmid mixed with 0.1% Fast Green were injected into the lateral ventricle of E15.5 embryo brains by pulled-glass micropipette
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In conclusion, targeting the gut microbiota is a novel therapeutic direction to improve CKD outcomes, and interventions such as probiotics to modulate the gut microbiota may provide new insights into individualized CKD treatment
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