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Apart from the common ICI monoclonal antibody-based drugs, monocyte-derived vaccines or dendritic cells (DC) loaded with tumour-associated antigens gp100 are also part of the immuno-oncology armamentarium
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Studies on human facial skin fibroblasts have shown that the amount of proteins modified by 4-HNE clearly increases with cellular age, indicating that 4-HNE may serve as a marker of oxidative damage accumulation in the skin [43]
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