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Product Specifications Test Results Sample: Cagrilinitide, Semaglutide 5/5mg Cagrilintide Properties Source: PubChem Form: Lyophilized powder Unit size: 2.5,5mg/vial Unit quantity: 1 vial Molecular formula: C 194 H 312 N 54 O 59 S 2 Molecular weight: 4409 g/mol Sequence: XKCNTATCATQRLAEFLRHSSNNFGPILPPTNVGSNTP CAS number: 1415456-99-3 Semaglutide Properties Source: PubChem Form: Lyophilized powder Unit size: 2.5/5mg/vial Unit quantity: 1 vial Molecular formula: C 187 H 291 N 45 O 59 Molecular weight: 4114 g/mol Synonym: NN9535 Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH CAS number: 910463-68-2 Frequently Asked Questions Related Products 3 of 48 products BPC-157 (10mg or 20mg) Tesamorelin SemagIutide (GLP-1 Analogue) How It Works Precision Synthesis Synthesized in dedicated, state of-the-art facilities

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When testing each drug type separately, we estimate the effect of the SNP on ΔBMI % to be larger in tirzepatide (effect = −0.95%) than semaglutide (effect = −0.51%), although the 95% confidence intervals were overlapping (Extended Data Fig