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Interestingly, GSH-depleted mice displayed a significantly elevated respiratory exchange ratio (RER) (Figure 1G), indicating increased carbohydrate utilization
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Mass spectrometry revealed that tetraspanins were enriched in migrasomes, and studies have confirmed the necessity of tetraspanins and cholesterol for migrasome formation through live-cell experiments and reconstituted membrane systems (Huang et al., 2019)
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