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However, what is less recognized is that the original erastin-mediated ferroptosis induced a mitochondria-independent oxidant stress, causing cell death, did not trigger cellular ATP depletion, and the morphology of the mitochondria indicates that they are smaller and denser, not swollen as is generally observed during necrotic cell death [13]

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68 Iron–sulfur clusters Biogenesis There are three classes of iron–sulfur cluster assembly systems used in prokaryotes, namely ISC, NIF, and SUF

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