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The irony: if you actually believe the proposed mechanisms, you should be worried more and not less Peter points out, “ Proangiogenic VEGF and nitric oxide signaling are exactly the kinds of pathways that potentiate tumor biology, abnormal vascular growth and tissue remodeling .” And of course that doesn’t prove that BPC-157 causes cancer (and Peter’s not saying that) But if proponents claim that it meaningfully stimulates healing through those pathways, they should also take seriously the possibility of stimulating biology you may not want overstimulated The trade-off is poor An unquantified benefit for injury, recovery, pain, inflammation, gut health, or performance, against an incompletely characterized molecule with unknown dosing, unknown human exposure, limited long-term safety data, and biologically plausible cancer related concerns That’s just not a trait Peter thinks most rational individuals would make Question #5: Is there a better characterized way to get the same result

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10.1126/scitranslmed.aau7356 231 ParpuraV.HaydonP