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The SAR showed that the presence of a 4-hydroxyl group on the phenyl ring of analogue , a 2,4-dihydroxyl moiety on the phenyl ring of scaffold , (Figure 8) and a 3-hydroxy-4-methoxyl group on the phenyl ring of compound (Figure 8) were responsible for their potent mTYR inhibitory activity [62]

Focus_Digestive

Concentration:0.5% w/v

10.4061/2011/925050 233 PandianN.KannegantiT