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The prevalence of vitiligo is quite variable around the world, being more frequent in Africa (0.4%), Europe (0.4%), and Oceania (1.2%), than in North America (0.2%) and Asia (0.1%).1 In Brazil, its prevalence varies between 0.46%–0.68% of the population, with no discrepancy between the sexes or racial groups

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Although potentially a more complicated connection with the gut microbiome and GH/IGF-1 axis compared to ghrelin, these studies further suggest a possible bidirectional relationship between the gut microbiota and hormones upstream of the GH/IGF-1 axis