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MOTS-c research, by contrast, consistently ties AMPK activation to improved glucose uptake and insulin sensitivity in skeletal muscle models, positioning it closer to metabolic health research on blood sugar regulation than to fat-cell-specific lipolysis
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For LC separation, tryptic peptides were sequentially injected into an Acclaim PepMap 100 C18 column (100 μM × 2 cm, 5 μM, Thermo Fisher Scientific) and an Acclaim PepMap 100 C18 column (50 μM × 15 cm, 2 μM, Thermo Fisher Scientific)
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