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Accumulating evidence suggests PINK1 as a key regulator of mitochondrial quality control, supporting preservation of mitochondrial respiration through cristae stabilization, phosphorylation of chaperones and possibly regulation of mitochondrial transport or mitophagy [312–315]
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Although exogenous administration of apolipoprotein A-IV was quite effective concerning meal size, food intake, and weight gain reduction in rats (190), data is lacking regarding apo A-IV therapeutic administration in humans and its effects on body weight
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