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(2012) analyzed DNA methylation in the liver tissue of rats with CCl 4 -induced liver fibrosis and demonstrated that hypomethylation/high expression of the Spp1 gene activates the PI3K/AKT pathway, inducing HSC activation and ECM secretion
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Several studies show that the composition of the gut flora of individuals with TS differs from that of the normal population, particularly in the number and species of certain bacterial strains
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