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One mechanism underlying these benefits is the activation of adenosine A₁ receptors by paeoniflorin: A₁ receptor stimulation has neuroprotective effects, and paeoniflorin’s ability to activate this pathway is linked to reduced neuroinflammation and improved dopamine neurotransmission in toxin-induced PD models (37)
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As an inactive form, DRP-104 preferentially converts to DON within tumors [186]
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