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thioredoxin-interacting protein (TXNIP), a master regulator of cellular redox that exerts an inhibitory action on thioredoxin, one of the major thiol antioxidants, with consequent increase in ROS concentration, and activates NLRP3 [138,140]
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In several instances, the deficiency of plasminogen has shown to cause a decrease in the recruitment of macrophages [94,95]
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