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PIMT1 methylates L-isoaspartyl moieties to form a L-isoaspartyl methyl ester, which (through a succinimide intermediate) can then spontaneously hydrolyze to aspartate (30% of the time), but can also revert back into a L-isoaspartyl group (70% of the time), requiring another round of methylation for repair

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Why it helps: contains trace selenium, a critical structural element for glutathione-dependent enzymes to function