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Usually, pro-oxidants and anti-oxidant mechanisms normally occur in a balanced state where biological oxidation reactions can cautiously take place, but if this balance is altered as a result of excess generation of ROS or a lack of antioxidant defense, it would lead to the oxidation of substrates in an uncontrolled manner and cause changes pathologically [11]
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( Though not as robust, right temporal and left parahippocampal gyri also showed significant functional connectivity with the above structures
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