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Subsequent reports from the Glass laboratory at Novartis, and others including us [29,83,84] revealed that the SomaMER and monoclonal antibody used in these initial studies cross-react with GDF8
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An early study revealed no changes in iron or transferrin levels in the CSF between MS and controls [73], while CSF/serum ferritin levels were significantly elevated in chronic progressive MS patients compared to controls and RR patients [43,73]
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