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It is considered as a region distinguished in space and function, which is comprised by different cell populations, namely, cancer cells, epithelial cells, extracellular matrix, stromal fibroblasts, immune cells (lymphocytes, macrophages, and mast cells), and vascular cells (endothelial, pericytes, and smooth muscle cells) ( EIF4A2 ), and Ribosomal protein L37 ( RPL37 ) involved in supporting translation process, cell survival and invasion ( An interesting example comes from the 26S proteasome non-ATPase subunit 4 ( PSMD4 ) gene, which encodes a ubiquitin-binding protein and constitutes one of the major ubiquitin receptor of 26S proteasome

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Studies of the insulin-like actions of thiols upon isolated fat cells