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Iron is an indispensable element in life activities and participates in many biological processes, such as DNA synthesis, energy metabolism, and signal transduction
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However, CYP2D6 is highly susceptible to inhibition by several commonly used medications, and the expected phenotype based on genotype alone could be erroneous if concomitant use of CYP2D6 inhibitors is not considered while predicting the CYP2D6 phenotype[7,8]
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