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Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial ...
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The ability of NAC to protect against the cardiovascular complications associated with diabetes was addressed in a recent systematic review that identified 49 papers reporting on in vitro and in vivo studies investigating the cardiac effects of NAC, mostly in animal models of diabetes [175]
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