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Patients will still need to be monitored for both local effects (mucosal changes or olfactory disturbances) and any systemic absorption effects (e.g., serum iron and blood counts) when intranasal chelation is tested in clinical studies

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Density barrier solution preparation 2b-1 NycodenzⓇ To make up the density barrier solution place 50 ml of Solution A, which contains 0.26 M NaCl, 6 mM KCl, 0.6 mM CaNa2EDTA, 10 mM Tricine-HCl, pH 7.2