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Palmitoylation of pyroptosis-related proteins is likewise closely associated with the onset and progression of IBD
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“The most exciting part of this work,” said McCall, “is that it demonstrates a new therapeutic approach with the potential to be disease-modifying for IPF.” Analysis of scRNA-seq data from patients with IPF and a mouse model of repeated injury to lung epithelium revealed persistent activation of hypoxia-inducible factor (HIF) signaling in fibrosis-associated aberrant (abnormal) epithelial cells
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