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Depletion of GSH (by BSO or diethylmaleate) also inhibits macrophage leishmanicidal activity, as well as NO production, while the GSH precursor GSH-ethyl ester restores them, 79 suggesting that the requirement for the GSH/NO pathway might be a common feature of resistance to intracellular pathogens
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Lactylation and metabolism Metabolism regulates glycolysis, OXPHOS, and other metabolic pathways by modulating gene expression and signaling pathways [45]
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