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Consequently, they have observed that propolis increased the life span across 93 days of mutant Drosophila melanogaster flies compared using levodopa only, although it was not as high as that in the propolis monotherapy and wild-type group, suggesting propolis may help lower the toxicity of levodopa in high dose

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Studies of glyoxalase 1-linked Multidrug resistance reveal Glycolysis-derived reactive metabolite, Methylglyoxal, is a common contributor in cancer chemotherapy targeting the Spliceosome