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However, it should be noted that current evidence regarding amino acid metabolism-mediated regulation of macrophage polarization is derived mainly from in vitro macrophage models and animal experiments, whereas systematic validation in human diseases remains relatively limited

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As regards the anthropometric measurements, the current study showed significant increase in weight z-score and height z-score with non-significant change in BMI z-score after 3 months of KD initiation (with P-values of 0.002, 0.002 and 0.06 respectively)