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LNPs are self-assembled from ionizable lipids, neutral helper lipids, and cholesterol to form a lipid core, while PEG-conjugated phospholipids are incorporated on the particle surface
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For example, CRT and other DAMPs can be used to enhance the efficacy of DC vaccines, or IL-10 signaling can be blocked to reverse the immunosuppressive microenvironment, thereby optimizing the anti-tumor immune response (210)
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