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5.4 Clinical evidence: melatonin in ART cycles and PCOS-related infertility Clinical data on melatonin as an adjunct in assisted reproduction (and specifically in PCOS) converge on a plausible benefit for intermediate outcomes, with more cautious signals for hard endpoints
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It is commonly employed in longevity and age-related signaling models, where researchers examine endpoints such as gene expression patterns, cellular stress responses, and telomere-related pathways in preclinical or in vitro systems
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