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Methylcobalamin is also contraindicated in patients with cobalt hypersensitivity because methylcobalamin contains cobalt
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Additionally, other researchers have observed deposition of type I collagen in the smooth muscle cells of coronary arteries of CD38 KO mice, but found that CD38 deficiency did not affect the expression of type I collagen protein and mRNA, indicating that CD38 regulates the degradation of type I collagen by inhibiting autophagosome and lysosomal fusion [34]
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