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In acute ischemic stroke, TrkB mediates pro-survival signaling while p75NTR mediates pro-apoptotic signaling, and the therapeutic strategy involves activating TrkB signaling and inhibiting p75NTR signaling (Alnoaman et al., 2025)
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LXRs are involved in the regulation of important metabolic pathways such as cholesterol homeostasis, glucose homeostasis, and lipogenesis in both humans and rats [185]
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