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Finally, although the correlations between the metabolome and microbiome were established using robust statistical analyses, there was limited statistical power and there are also limitations to the statistical approaches used herein (e.g., log transformation to resolve non-normal distribution and/or heteroscedasticity 103 )

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If the lipolytic activity of growth hormone genuinely lives in a discrete domain, the domain in question is a constrained loop presented on a folded surface, not a floppy linear peptide