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Downstream of MET activation the signaling is well characterized and is not in dispute as general biology: MET phosphorylation recruits GAB1 and GRB2 and drives PI3K/AKT and MAPK/ERK cascades
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Although the precise mechanism through which cerebrolysin promotes increased BDNF production and downregulates microglial activation after a seizure remains unclear, the present study suggests that the administration of cerebrolysin can be a useful therapeutic agent to prevent neuronal death in this setting
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