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The positive signals identified through signal detection were compared with the adverse events mentioned in the FDA-approved label to identify any unmentioned adverse events

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However, another study using different PepMV isolates reported no synergistic effects between ToBRFV and PepMV, but rather additive ones, indicating that the specific PepMV isolate plays a critical role in the outcome of mixed infections (Hernando and Aranda 2024)