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Biochemical effects and mechanisms of toxicity 7.3.1
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also found that the occurrence of cuproptosis was significantly related to mitochondrial metabolism, providing a more plausible mechanism for explaining the anti-cancer effect of ES depending on the transport of extracellular copper ions and the mitochondrial respiration intensity of cancer cells ( The metabolic selectivity of elesclomol may provide a reference for the treatment of specific metabolic-type tumors as a targeted therapy (210)
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